Fragile X

Definition Fragile X syndrome (FXS) is now the most gross know get cause of develop psychic disabilities, just now was not discovered until the new-fangled 1970s. By 1980 it was found that people present certain mental and physical characteristics had a chromosomal constipation caused by a partial break on an X chromosome, c each(prenominal)ed a little(a) site. In 1991 the Fragile X cistron was set within this site. FXS is named after a site on the commodious arm of the X chromosome that is elongated and appears partly mazed or fragile. The spectrum of Fragile X syndrome ranges from normal development to developmental tick, development disabilities, fruity to fearsome intellectual disability, autistic-like behaviour and attentional problems. The volume of children are mildly to moderately unnatural. There may or may not be other known affected family members. Genetic testing has changed the approach to the diagnosis of the antecedent because in that respect is no w a reliable and comparatively simple breed detection test which is available to all children with developmental delay of unknown cause. The diagnosis of FXS is important to apply effective charge and interventional strategies. Detection of carriers allows families to make informed decisions quest contagious counselling. Incidence Estimates call forth near 1 in 4,000 males are affected and that about 1 in 1,000 females carry the gene.

Many affected family members are unaware of the genetic cause and have yet to be diagnosed. In comparison, 1 in 700 live births has Downs syndrome (which is not ordinarily inheri ted). The Fragile X Syndrome The clinical fe! atures of Fragile X syndrome allow in physical, developmental and behavioural characteristics and range from normal through mild to severe in stateation. Intellectual disability (IQ less than 70) is present in 80% of males and 50% of females. Children may have been denominate as having pervasive developmental disorder, Aspergers syndrome, If you want to get a estimable essay, order it on our website: OrderCustomPaper.com

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